Early dose response analysis of ocular hypotensive effects of propranolol in patients with ocular hypertension.
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چکیده
منابع مشابه
Propranolol as ocular hypotensive agent.
AHLQUIST (1948) suggested that adrenergic activity is divisible into alpha and beta groups. The former is concerned mainly with contraction of smooth muscle, including vasoconstriction in some areas-noradrenaline is almost exclusively an alpha substance. The latter includes adrenergic effects on the heart and relaxation of bronchial muscles-isoprenalin restricts itself almost entirely to such a...
متن کاملAtenolol versus propranolol A comparison of ocular hypotensive
Both atenolol and propranolol by mouth reduce ocular tension in normal and glaucomatous eyes (Phillips, Howitt, and Rowlands, i967; Elliot, Cullen, and Phillips, 1975; Wettrell and Pandolfi, 1975). These drugs are f-adrenergic blockers but propranolol affects both P1 and 32 receptors (as well as having a 'membrane' effect), while atenolol is a more specific 31 receptor antagonist and lacks the ...
متن کاملAtenolol versus propranolol. A comparison of ocular hypotensive effect of an oral dose.
In a controlled double-blind cross-over trial in 10 patients comprising six with open-angle glaucoma, three with closed-angle glaucoma, and one with ocular hypertension, a single oral dose of atenolol (50 mg) was significantly more effective than propranolol (40 mg) in reducing ocular tension.
متن کاملOcular hypotensive effect of the Rho kinase inhibitor AR-12286 in patients with glaucoma and ocular hypertension.
PURPOSE To evaluate the ocular hypotensive efficacy of 0.05%, 0.1% and 0.25% AR-12286 Ophthalmic Solutions in patients diagnosed with ocular hypertension or glaucoma. DESIGN Parallel comparison, vehicle-controlled, double-masked, 3-week randomized clinical trial. METHODS Subjects (n = 89) with elevated intraocular pressure (IOP) were assigned randomly to receive either 1 of 3 concentrations...
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ژورنال
عنوان ژورنال: British Journal of Ophthalmology
سال: 1976
ISSN: 0007-1161
DOI: 10.1136/bjo.60.10.680